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by Internet Medical Society

Can Femara (Letrozole) be used for Treating Infertility in PCOS ?

Dr. Uday Thanawala(Gynecologist and Fertility Expert) Discuss about the Femara (letrozole) for treating fertility in PCOS

Femara (letrozole) is an oral medication used to stimulate ovulation in women with polycystic ovary syndrome (PCOS) and unexplained infertility. Fertility drugs are used often in infertility treatments. There are two situations in which fertility drugs may be useful. First, these drugs can be used to induce an egg to develop and be released in women who are not ovulating on their own. This is known as ovulation induction. Fertility drugs can also be used to increase the chances of pregnancy in women who are already ovulating.

The findings convincingly showed that for women with PCOS:

  • The ovulation rate was superior with letrozole (61.7%) than with Clomid (48.3%)
  • The cumulative live birth rate was higher with letrozole (27.5%) the with Clomid (19.5%)
  • The live birth benefit was higher in obese women (BMI ≥ 35)
    letrozole was equal or superior to Clomid at all BMI groups

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