Lenalidomide: Capsules for oral administration

[Mary Kudro]

The FDA approved the medicine Lenalidomide in 2005; it is an analog of thalidomide with immunomodulatory, antiangiogenic, and antineoplastic properties. Lenalidomide inhibits proliferation and induces apoptosis of certain hematopoietic tumor cells, including multiple myeloma, mantle cell lymphoma, and del (5q) myelodysplastic syndromes in vitro. This drug is sold under the brand name Revlimid. Lenalidomide comes as capsules in 5 mg, 10 mg, 15 mg and 25 mg for oral administration. The active ingredient in the capsules is Lenalidomide with inactive ingredients lactose anhydrous, microcrystalline cellulose, croscarmellose sodium, and magnesium stearate. Lenalidomide is an off-white to pale-yellow solid powder. It is soluble in organic solvent/water mixtures and buffered aqueous solvents.

Revlimid cost is reasonable in India with multiple generic medicine suppliers.