by Internet Medical Society
Infections to Cancer
Introduction
World Cancer Day 4 February, 2011 UICC/WHO
By the year 2020, there will be 16 million new cases of cancer/year, out of which 70% in developing countries.
Each year, over 12 million people receive a cancer diagnosis and 7.6 million die of the disease.
The good news is that approximately 40% of cancers are potentially preventable.
The risk of developing cancer can significantly be reduced through simple measures:
- Stop tobacco use and avoid exposure to second-hand smoke
- Limit alcohol consumption
- Avoid excessive sun exposure
- Maintain a healthy weight, through eating healthily and exercising regularly
- Protect against cancer-causing infections
Infections Causing Human Cancer. was 2007. Wiley-VCH: Weinheim. 532p. ISBN: (Hardcover) 9783527310562. US $215
- Aleksandar D. Kostic,
- Dirk Gevers,
- Chandra Sekhar Pedamallu,
- Monia Michaud,
- Fujiko Duke,
- Ashlee M. Earl,
- Akinyemi I. Ojesina,
- Joonil Jung,
- Adam J. Bass,
- Josep Tabernero,
- José Baselga,
- Chen Liu,
- Ramesh A. Shivdasani,
- Shuji Ogino,
- Bruce W. Birren,
- Curtis Huttenhower,
- Wendy S. Garrett,
- and Matthew Meyerson
Genome Res. Published in Advance October 18, 2011,doi:10.1101/gr.126573.111
- Mauro Castellarin,
- René L. Warren,
- J. Douglas Freeman,
- Lisa Dreolini,
- Martin Krzywinski,
- Jaclyn Strauss,
- Rebecca Barnes,
- Peter Watson,
- Emma Allen-Vercoe,
- Richard A. Moore,
- and Robert A. Holt
Genome Res. Published in Advance October 18, 2011,doi:10.1101/gr.126516.111
| AV Number: | AV-8000-0617 |
|---|
Electron Micrograph Epstein Barr Virus
From CDC PHIL 2982
Nobel Prize Awards in Infections and Cancer
Tumor Viruses
2. 1975 Nobel Prize in Medicine for interactions between tumor virus and host cells
| David Baltimore | |
|---|---|
 David L. Baltimore
|
|
| Born | 7 March 1938 New York City, New York, USA |
| Nationality | United States |
| Fields | Biology |
| Institutions | Massachusetts Institute of Technology Rockefeller University California Institute of Technology |
| Alma mater | Swarthmore College Rockefeller University |
| Known for | Reverse transcriptase |
| Notable awards | Nobel Prize in Physiology or Medicine(1975) |
http://en.wikipedia.org/wiki/David_Baltimore
http://baltimorelab.caltech.edu/
| Howard Martin Temin | |
|---|---|
 Howard Martin Temin
|
|
| Born | December 10, 1934 Philadelphia |
| Died | February 9, 1994 |
| Nationality | United States of America |
| Institutions | University of Wisconsin–Madison |
| Alma mater | California Institute of Technology |
| Known for | reverse transcriptase |
| Notable awards | 1975 Nobel Prize in Physiology or Medicine |
| Renato Dulbecco | |
|---|---|
 Renato Dulbecco
|
|
| Born | February 22, 1914 (age 95) Catanzaro |
| Nationality | Italy United States |
| Fields | Virologist |
| Institutions | California Institute of Technology Salk Institute London Research Institute |
| Alma mater | University of Turin |
| Known for | Reverse transcriptase |
| Notable awards | Nobel Prize in Physiology or Medicine in 1975 |
The Nobel Assembly at Karolinska Institutet has today decided to award
The Nobel Prize in Physiology or Medicine for 2008 with one half to
Harald zur Hausen
for his discovery of “human papilloma viruses causing cervical cancer”
and the other half jointly to
Françoise Barré-Sinoussi and Luc Montagnier
for their discovery of “human immunodeficiency virus”
| Harald zur Hausen | |
|---|---|
 |
|
| Born | March 11, 1936 (age 73) Gelsenkirchen, Germany |
| Nationality | German |
| Fields | Virology |
| Institutions | German Cancer Research Center |
| Known for | Discovery that HPV can causecervical cancer |
| Notable awards | 2008 Nobel Prize in Physiology or Medicine |
From NobelPrize.org
DISTRIBUTION OF CERVICAL CANCER
 |
The global public health burden attributable to human papilloma virus is considerable. More than 5% of all cancers worldwide are caused by persistent infection with this virus. Infection by the human papilloma virus is the most common sexually transmitted agent, afflicting 50-80% of the population.
| AV Number: | AV-8610-3067 |
|---|
Tumor Bacteria Helicobacter pylori
5. Robin Warren in 1979 first observed the bacteria in 50% of biopsy samples from patients who had died due to ulcer. A new biopsy study was done by Barry Marshall and Robin Warren in 100 Australian patients to confirm the earlier findings. The bacterium was isolated and cultured for the first time in 1982, Helicobacter pylori, bacteria on the surface of the gastric
The bacteria probably spread directly from person to person orally and is acquired during birth from mother to child. If an individual is not infected before the age of 10 years, he has very little risk of being later. Helicobacter pylori are detected in more than 90% of people with duodenal ulcers and in about 80% of those with gastric ulcer. Infection with Helicobacter pylori is one of the most chronic infections throughout the world: 20 to 90% of adults are infected in different countries. The infection is more common in developing countries (60 to 80% of the population affected), while it is lowest in the industrialized countries (20 to 50% of the population that is affected, especially those disadvantage).
A sharp rise in the elderly population is observed.
Lymphoma of MALT (Mucosa Associated Lymphoid Tissue) even rarer was his prognosis changed
since the knowledge of Helicobacter pylori.
NCI Visuals Online
| AV Number: | AV-8000-0285 |
|---|
Endoscopy Diagnosis
Worms causing Human Sufferings
Schistosomiasis and Bladder Cancer
Schistosomiasis, or bilharzia, is a parasitic disease caused by trematode flatworms of the genus Schistosoma.
In the body, the larvae develop into adult schistosomes, which live in the blood vessels. The females release eggs, some of which are passed out of the body in the urine or faeces.
In urinary schistosomiasis, there is progressive damage to the bladder, ureters and kidneys.
In intestinal schistosomiasis, there is progressive enlargement of the liver and spleen, intestinal damage, and hypertension of the abdominal blood vessels.
Control of schistosomiasis is based on drug treatment, snail control, improved sanitation and health education.
Schistosomiasis is a parasitic disease that occurs in tropical and subtropical areas of the world. It is the major health risk in the rural areas of Central China and Egypt and continues to rank high in other developing countries.
• Some 600 million people are at risk of becoming infected. It is estimated that 200 million people are already infected.
• Schistosomiasis contributes to 27.6% of bladder cancer. Over 350’000 new cases of bladder cancer are recorded worldwide.
• Extreme poverty, the unawareness of the risks, the inadequacy or total lack of public health facilities plus the unsanitary environment are all factors contributing to the risk of infection.
• Schistosomiasis is an avoidable risk factor which could reduce the burden of bladder cancer in developing
Schistosomiasis by Sherif El Saadany
Histopathological and Immune-Pathological Changes in the Prostates ...
http://www.who.int/wormcontrol/en/
- Chagas disease (Region of the Americas – PAHO)
http://www.paho.org/english/hcp/hct/dch/chagas.htm
CDC PHIL 11201
Schistosoma mansoni trematodes
Cancer Drugs#58 Books and MonographsCancer Drugs#58 Books and Monographs
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