by Internet Medical Society

Understanding Liver Transplant - Diagnosis and Treatment


The liver is among the vital organs of human body. If it fails due to any reason, it would be difficult for the patient to survive. The liver acts to some of the most critical functions of the body, which include drugs & toxins metabolism along with flushing out the degradation products of the normal body metabolism and synthesis apart from a number of key proteins and enzymes. When liver fails, you have an option called liver transplant, which is basically a surgical procedure, which is meant to replace the diseased liver of a patient with a healthy one from a donor who could be alive or dead.


The liver can fail in our body due to a number of reasons, which can lead to treatments like liver transplant. If a person is on the end state of liver failure, which cannot be fixed using any other treatment options or the people suffering from liver cancer then they need this procedure. In case of acute liver failure, this organ can fail immediately within a week’s time or for the chronic liver failure, this can take months and even years to stop working completely. This usually gives enough time to the patient to choose this surgical option called liver transplant. When it comes to causes behind the liver failure there are many. Some of the common causes of the liver failure are enlisted below, how about checking them as under:

  • Liver cirrhosis
  • Non alcoholic fatty liver disease
  • Alcoholic liver disease
  • The early stage liver cancer
  • Hemochromatosis
  • Primary sclerosing cholangitis
  • Primary biliary cirrhosis
  • Biliary duct atresia
  • Wilson's disease and
  • Cystic fibrosis


When it comes to symptoms there are couple, however, the following four are the common ones, which are worthy to be discussed here:

  • Gastrointestinal bleeding: As the liver becomes very much scarred, you can find the resistance to certain portal blood flow increasing. This increases the pressure within the portal venous system leading to hypertension that further disturbs the vein in the abdomen area giving this symptom to the patient.  
  • Fluid Retention: When liver fails, you can find the low albumin levels that simply push the bloodstream that are not able to get re-absorbed. Here you can find fluid accumulating over the tissues and other parts of the body leading to this symptom called fluid retention.
  • Encephalopathy: One of the important functions of liver is to make your body free from toxins and clear ammonia from the blood. However, failure of liver can hamper this function, which allows the toxins to become cognitive dysfunction that bring in this symptom.
  • Jaundice: This ailment is often the common symptoms of liver issues. This can take time to get back to normal life, however, if you fail to avert this ailment you are likely to face the failure of liver, hence jaundice is also considered to be early symptoms of the liver issues.


You can find three types of liver transplant, which are as under:

  • Orthotopic transplant: In this procedure the entire liver is considered from any deceased donor, which further replaces the damaged one by the surgeon. This is among the most common liver transplant found in sorting out the damaged liver issues.
  • Living donor transplant: In this procedure a living donor gives his or her liver for the patient. The surgeon then replaces the damaged one with the healthy liver donated mostly by the patient’s family member.
  • Split donation: In this procedure is carried out when any deceased person has donated to the patient. The surgeon splits the same into right and left lobes and later does the needful to finish the task of liver transplant.


Liver is one of the most important organs found in human body. It failure can even bring risks like death; however, the only solution for people with failed liver is to go with a procedure called liver transplant. 

Read More About:

Liver Transplant : What should You Know
Understanding Cirrhosis of the Liver - Topic Overview

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