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by Internet Medical Society

THYROID - DYSFUNCTION IN PATIENTS WITH TYPE 2 DIABETES IN GENERAL POPULATION

This study, published in Archives of Medicine, was undertaken with an objective to knowthe thyroid functions in Type 2 diabetics and to know the spectrum of thyroiddysfunction in Type 2 DM.Methods: A total of 100 patients with Type 2 DM who were diagnosed on thebasis of ADA criteria or who were taking treatment for Diabetes were included inthe study. All patients in the study underwent thyroid profile tests for the thyroidstatus and also target organ evaluation for Diabetes. TPO-Ab, thyroid USG andFNAC where done where ever required. A detailed history and examination wasdone on these patients.Results: A total of 100 Type 2 DM patients were included in the study. Thyroiddisorders were present in 29%. Hypothyroidism in 1, hyperthyroid in 13 and subclinicalhypothyroidism in 15 cases. In this study 50 patients were males and 50were females. Females (36%) had high incidence of thyroid disorders than males(22%). Sub- clinical hypothyroidism was more common among elderly (31.25%).Elderly females had high incidence of sub- clinical hypothyroidism (18.2%). Clinicalfeatures were present in 8 patients, all of them were diagnosed hyperthyroid. Otherpatients did not have any sings and symptoms. Patients with hyperthyroidism hada poor glycemic control 55.5% duration of diabetes had no relation with incidenceof thyroid disorders. Patients with severe diabetic micro vascular complication hadsub- clinical hypothyroidism.Conclusion: prevalence of thyroid disorders in Diabetics was 29%. Elderly populationhad more incidence than those below sixty. Sub-clinical hypothyroidism wasmore common among females. Diabetics with hyperthyroidism had poor glycemiccontrol. Severe diabetic complications where noted in patients with sub- clinicalhypothyroidism. Duration of Diabetes had not impact on thyroid dysfunction.

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